Cédric - Thursday, February 6, 2025

This technique allows detecting viruses by... their noise 🎧

What if viruses emitted sounds imperceptible to the human ear, but revealing of their identity? Researchers at Michigan State University have developed an innovative method to listen to these vibrations, paving the way for faster and less invasive viral detection.


This approach relies on the analysis of the natural vibrational frequencies of viruses, a kind of unique acoustic fingerprint. Unlike traditional techniques, it requires neither chemical labeling nor complex equipment. This discovery could transform the way we diagnose and monitor viruses, particularly in public or medical environments.

The limitations of current methods


Current viral detection tests, such as PCR, although accurate, are costly and time-consuming to perform. They require biological samples and specialized equipment, limiting their use in urgent or large-scale contexts. Antigen tests, while faster, often lack sensitivity, which can lead to diagnostic errors.

These constraints have pushed scientists to explore alternatives. The new method, based on the natural vibrations of viruses, could overcome these obstacles by offering rapid, accurate, and non-invasive detection, without the need for complex sampling.

Listening to viruses: an innovative method



Viruses, like all biological particles, vibrate at specific frequencies depending on their structure and environment. Using ultrafast spectroscopy, researchers were able to observe these vibrations at the nanoscale. These oscillations, in the gigahertz range, are far too high to be perceived by the human ear.

This technique, called BioSonics spectroscopy, allows for the detection of individual viruses without chemical labeling. It reveals information about their morphology and interactions with the environment, offering a new perspective on their mechanical and biological behavior.

Promising applications


One of the applications of this discovery is the real-time detection of viruses in the air. Sensors could be deployed in public places, hospitals, or transportation, enabling continuous monitoring and a rapid response in case of viral presence.

Moreover, this method is inexpensive and works under ambient conditions, making it accessible for rapid diagnostics. It could also reduce the risks of contamination and human error, while providing immediate results.

To go further: How does BioSonics spectroscopy work?


BioSonics spectroscopy is a technique that analyzes the natural vibrations of viruses at the nanoscale. Each virus has its own frequency, influenced by its structure and environment, forming a unique acoustic signature detectable by this method.

To capture these vibrations, researchers use ultrafast laser pulses. These light beams generate mechanical waves that interact with viral particles, allowing the measurement of their oscillations in the gigahertz range, invisible to classical techniques.

One of the major advantages of BioSonics is its non-invasive nature: no chemicals or reagents are required. This approach simplifies virus identification in real-time and reduces the constraints associated with traditional biological sampling.

Already tested in the laboratory, this technology could be integrated into portable sensors to continuously monitor ambient air. Its effectiveness opens the way to early detection systems, essential for limiting the spread of viral infections.

Article author: Cédric DEPOND
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