At the heart of our cells, a previously unknown structure has just been identified, shedding new light on essential biological mechanisms. This discovery could transform our understanding of certain genetic diseases.
Research conducted by an American team reveals the existence of a previously unknown organelle, named the hemifusome. Using cutting-edge imaging techniques, scientists were able to observe its key role in managing cellular resources.
Three images showing the newly discovered organelle, the hemifusome. An overlooked player in cellular logistics
Hemifusomes act as sorting platforms, facilitating the formation and transport of vesicles. These vesicles serve as vehicles to distribute molecules necessary for proper cell function.
According to research published in
Nature Communications, these transient structures appear near the cell membrane. Their presence suggests involvement in processes as varied as waste recycling or the assembly of other organelles.
Malfunctions of hemifusomes could explain certain pathologies. Hermansky-Pudlak syndrome, a rare disease affecting multiple organs, is one example.
Promising therapeutic prospects
The discovery opens new avenues for treating neurodegenerative diseases like Alzheimer's. Understanding how these organelles interact with vesicles could lead to targeted interventions.
Researchers emphasize that this breakthrough is just a first step. Future studies will need to clarify the exact role of hemifusomes in different pathological conditions.
This structure, though recently identified, appears ubiquitous. Its in-depth study could reveal previously unsuspected cellular mechanisms.
Article author: Cédric DEPOND